Suppose It’s Not “Alternative”
—It’s Advanced.

Let’s get one thing clear: this isn’t some fringe theory—it’s legit biology, backed by decades of research. Your body already has a whole network of receptors designed to help regulate pain, stress, inflammation, mood, and more.

We’re not here to sell pseudoscience—we’re here to explain how THC-A, terpene-rich hemp, and suppository delivery activate your body in all the right places. No fluff, no hype—just researched, real science working to support relief, pleasure, and balance from the inside out.

Meet Your ECS

Your endocannabinoid system (ECS) is a vast, built-in regulatory network that helps your body maintain homeostasis—or balance—across essential functions like mood, inflammation, pain response, sleep, immune health, appetite, and even reproductive function. It’s made up of three key components: endocannabinoids, cannabinoid receptors (CB1 and CB2), and enzymes that break down these compounds once they’ve done their job.

CB1 receptors are concentrated in the brain and central nervous system, while CB2 receptors are more active in the immune system and peripheral tissues—including the pelvic region. These receptors act like locks, and endocannabinoids are the keys your body naturally produces.

One of the most well-known of these is anandamide—nicknamed “the bliss molecule”—a neurotransmitter that plays a role in managing pain, pleasure, and stress relief.

Cannabis compounds like THC-A can interact with this same system, mimicking or enhancing the effects of your body’s natural endocannabinoids to support relief, relaxation, and repair.
THC-A: Pelvic Relief’s It-Girl

Your endocannabinoid system (ECS) is a vast, built-in regulatory network that helps your body maintain homeostasis—or balance—across essential functions like mood, inflammation, pain response, sleep, immune health, appetite, and even reproductive function. It’s made up of three key components: endocannabinoids, cannabinoid receptors (CB1 and CB2), and enzymes that break down these compounds once they’ve done their job. CB1 receptors are concentrated in the brain and central nervous system, while CB2 receptors are more active in the immune system and peripheral tissues—including the pelvic region. These receptors act like locks, and endocannabinoids are the keys your body naturally produces.

One of the most well-known of these is anandamide—nicknamed “the bliss molecule”—a neurotransmitter that plays a role in managing pain, pleasure, and stress relief. Cannabis compounds like THC-A can interact with this same system, mimicking or enhancing the effects of your body’s natural endocannabinoids to support relief, relaxation, and repair.
Terpenes, Explained (And Why Ours Do the Damn Thing)

Terpenes are aromatic compounds found in plants—including cannabis—that influence how cannabinoids like THC-A interact with your body. They’re not just for scent; they play a huge role in how you feel.

Our formula is built around what’s called a “blue” terpene profile—featuring calming, anti-inflammatory terpenes found in plants like lavender, chamomile, and blue tansy.

Terpenes are aromatic compounds found in plants—including cannabis—that influence how cannabinoids like THC-A interact with your body. They’re not just for scent; they play a huge role in how you feel.

Our formula is built around what’s called a “blue” terpene profile—featuring calming, anti-inflammatory terpenes found in plants like lavender, chamomile, and blue tansy.
The Suppository Glow-Up

Let’s talk delivery. Suppositories are one of the most efficient ways to get relief exactly where it’s needed—especially when it comes to pelvic discomfort.

By bypassing the digestive system, THC-A avoids liver breakdown and heads straight for local ECS receptors. That means higher absorption, faster effects, and fewer side effects.

In other words: smarter, smoother, and made to work from the inside out.

The science is emerging.
And it’s real.

We’re still in the early days of cannabinoid research—especially when it comes to vaginal and rectal health. But early doesn’t mean unproven. The endocannabinoid system is a legitimate, complex part of human biology, and THC-A is showing real promise across a range of conditions. We’ve curated a library of peer-reviewed articles and reputable resources so you can see the science for yourself—whether you’re curious, skeptical, or ready to become an expert.

Suppose you had the full picture.

Our founder Dr. Lynn has created a guide that breaks down how Suppose works and the conditions it may support—all in one clear, science-backed read.

Download the Guide

Explore the research

How THC-A Works in the Body(And Why It’s Not Just “Weed”)

Let’s Clear Something Up THC-A is not the same as THC. And taking a THC-A suppository is not the same thing as getting high. So what is it, exactly?Let’s break it down.First Things First: What Is THC-A?THC-A stands for tetrahydrocannabinolic acid—it’s the raw, unheated, non-psychoactive form of THC that exists naturally in the cannabis plant. […]

Marijuana, the Endocannabinoid System

This review explores how cannabis compounds interact with the body’s endocannabinoid system, potentially influencing female reproductive hormones, menstrual cycles, and fertility.

Marijuana, the Endocannabinoid System, & the Female Reproductive System